|
|
S-adenosyl-L-methionine + caffeoyl-CoA <=> H+ + feruloyl-CoA + S-adenosyl-L-homocysteine
|
2.1.1.104
caffeoyl-CoA O-methyltransferase
|
–
|
BMK
|
|
BRENDA:
BR43863
KEGG:
R01942
MetaCyc:
CAFFEOYL-COA-O-METHYLTRANSFERASE-RXN
|
|
|
|
caffeoyl-CoA + isocitrate <=> 2-caffeoylisocitric_acid + CoA
|
2.3.1.126
isocitrate O-dihydroxycinnamoyltransferase
|
–
|
|
|
BRENDA:
BR43987
KEGG:
R01946
MetaCyc:
2.3.1.126-RXN
|
|
|
|
putrescine + caffeoyl-CoA <=> H+ + N-caffeoylputrescine + CoA
|
2.3.1.138
putrescine N-hydroxycinnamoyltransferase
|
–
|
|
|
BRENDA:
BR43998
KEGG:
R01944
MetaCyc:
2.3.1.138-RXN
|
|
|
|
3,4-dihydroxyphenyllactic_acid + caffeoyl-CoA <=> rosmarinic_acid + CoA
|
2.3.1.140
rosmarinate synthase
|
–
|
MK
|
|
BRENDA:
BR44001
KEGG:
R03374
MetaCyc:
RXN-7633
|
|
|
|
3,4-dihydroxyphenylpropanoyl-CoA + NAD+ + reduced_ferredoxin_[iron-sulfur]_cluster <=> caffeoyl-CoA + NADH + oxidized_ferredoxin
|
1.3.1.108
caffeoyl-CoA reductase
|
–
|
|
|
BRENDA:
BR51443
KEGG:
R11674
MetaCyc:
RXN-16702
|
|
|
|
3,4-dihydroxyphenylpropanoyl-CoA + caffeic_acid <=> 3,4-Dihydroxyphenylpropionate + caffeoyl-CoA
|
2.8.3.23
caffeate CoA-transferase
|
–
|
|
|
BRENDA:
BR51451
KEGG:
R11206
MetaCyc:
RXN-16745
|
|
|
|
caffeic_acid + CoA + ATP <=> caffeoyl-CoA + AMP + diphosphate
|
6.2.1.12
4-coumarate---CoA ligase
|
–
|
BMK
|
|
BRENDA:
BS26
KEGG:
R01943
MetaCyc:
RXN-1126
SABIO-RK:
12842;
1996
|
|
|
|
trans-5-O-caffeoylshikimate + CoA <=> caffeoyl-CoA + shikimate
|
2.3.1
2.3.1.133
shikimate O-hydroxycinnamoyltransferase
2.3.1.99
quinate O-hydroxycinnamoyltransferase
|
–
–
–
|
BMK
|
|
BRENDA:
BS320440
KEGG:
R07433
MetaCyc:
RXN-2621
|
|
|
|
chlorogenic_acid + CoA <=> caffeoyl-CoA + quinate
|
2.3.1
2.3.1.133
shikimate O-hydroxycinnamoyltransferase
2.3.1.99
quinate O-hydroxycinnamoyltransferase
|
–
–
–
|
BMK
|
|
BRENDA:
BS321558
KEGG:
R01945
MetaCyc:
RXN-2622
|
|
|
|
caffeoyl-CoA + H2O <=> 3,4-Dihydroxybenzaldehyde + acetyl-CoA
|
4.1.2.61
feruloyl-CoA hydratase/lyase
|
–
|
|
|
BRENDA:
BS368234
MetaCyc:
RXN-21005
|
|
|
|
caffeoyl-CoA + serotonin <=> (2E)-3-(3,4-dihydroxyphenyl)-N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]prop-2-enamide + CoA + H+
|
2.3.1.110
tyramine N-feruloyltransferase
2.3.1.M35
|
–
–
|
M
|
|
BRENDA:
BS376441
MetaCyc:
RXN-8709
|
|
|
|
caffeoyl-CoA + (S)-malate <=> phaselic_acid + CoA
|
2.3.1.133
shikimate O-hydroxycinnamoyltransferase
|
–
|
M
|
|
BRENDA:
BS408813
MetaCyc:
RXN-10825
|
|
|
|
cyanidin_3-O-beta-D-glucoside + caffeoyl-CoA <=> cyanidin_3-O-(6''-caffeoyl)-beta-D-glucoside + CoA
|
2.3.1.215
anthocyanidin 3-O-glucoside 6''-O-acyltransferase
|
–
|
MK
|
|
BRENDA:
BS423093
KEGG:
R07928
MetaCyc:
RXN-16783
|
|
|
|
pelargonidin_3-O,5-O-di-beta-D-glucoside + caffeoyl-CoA <=> pelargonidin_3-O-(6-caffeoyl-beta-D-glucoside)_5-O-beta-D-glucoside + CoA
|
2.3.1
2.3.1.215
anthocyanidin 3-O-glucoside 6''-O-acyltransferase
|
–
–
|
MK
|
|
BRENDA:
BS423098
KEGG:
R07876
MetaCyc:
RXN-8138
|
|
|
|
caffeoyl-CoA + 2-oxoglutarate + O2 <=> 6'-hydroxycaffeoyl-CoA + succinate + CO2
|
1.14.11
1.14.11.61
feruloyl-CoA 6-hydroxylase
|
–
–
|
M
|
|
BRENDA:
BS447257
MetaCyc:
RXN-16762
|
|
|
|
delphinidin_3,5-di-O-beta-D-glucoside + caffeoyl-CoA <=> delphinidin_3-O-beta-D-glucosyl-5-O-(6-O-caffeoyl-beta-D-glucoside) + CoA
|
2.3.1.153
anthocyanin 5-(6'''-hydroxycinnamoyltransferase)
|
–
|
MK
|
|
BRENDA:
BS7663
KEGG:
R07944
MetaCyc:
RXN-8233
|
|
|
|
caffeoyl-CoA + NADPH <=> caffeoyl_aldehyde + CoA + NADP+
|
1.2.1.44
cinnamoyl-CoA reductase
|
–
|
K
|
|
BRENDA:
BS189228
KEGG:
R01941
SABIO-RK:
1994
|
|
|
|
caffeoyl-CoA + delphinidin_3-O-beta-D-glucoside <=> CoA + delphinidin_3-O-[6-O-caffeoyl-beta-D-glucoside]
|
2.3.1.215
anthocyanidin 3-O-glucoside 6''-O-acyltransferase
|
–
|
K
|
|
BRENDA:
BS423095
KEGG:
R07926
|
|
|
|
cyanidin_3,5-di-O-beta-D-glucoside + caffeoyl-CoA <=> CoA + cyanidin_3-O-beta-D-glucoside-5-O-(6-O-caffeoyl)-beta-D-glucoside
|
2.3.1.153
anthocyanin 5-(6'''-hydroxycinnamoyltransferase)
|
–
|
K
|
|
BRENDA:
BS7664
KEGG:
R07931
|
|
|
|
pelargonidin_3-O,5-O-di-beta-D-glucoside + caffeoyl-CoA <=> Pelargonidin_3-glucoside_5-caffeoylglucoside + CoA
|
2.3.1.153
anthocyanin 5-(6'''-hydroxycinnamoyltransferase)
|
–
|
K
|
|
KEGG:
R07930
MetaCyc:
RXN-7842
|
|
|
|
pelargonidin_3-O-beta-D-glucoside + caffeoyl-CoA <=> Pelargonidin_3-O-(6-caffeoyl-beta-D-glucoside) + CoA
|
2.3.1
2.3.1.215
anthocyanidin 3-O-glucoside 6''-O-acyltransferase
|
–
–
|
MK
|
|
KEGG:
R07873
MetaCyc:
RXN-7997
|
|
|
|
caffeoyl-CoA + tryptamine <=> CoA + (2E)-3-(3,4-dihydroxyphenyl)-N-[2-(1H-indol-3-yl)ethyl]prop-2-enamide
|
2.3.1.110
tyramine N-feruloyltransferase
|
–
|
|
|
BRENDA:
BS376443
SABIO-RK:
14779
|
|
|
|
4-coumaroyl-CoA <=> caffeoyl-CoA
|
1.14.13
|
–
|
K
|
|
KEGG:
R07436
|
|
|
|
caffeoyl-CoA + 3 malonyl-CoA <=> 2',3,4,4',6'-pentahydroxychalcone + 4 CoA + 3 CO2
|
2.3.1.74
chalcone synthase
|
–
|
K
|
|
KEGG:
R07988
|
|
|
|
caffeoyl-CoA + spermidine <=> CoA + N1,N5,N10-Tricaffeoyl_spermidine + H+
|
2.3.1.M34
|
–
|
M
|
|
MetaCyc:
RXN-11258
|
|
|
|
pelargonidin_3-O-beta-D-sambubioside + caffeoyl-CoA + H+ <=> pelargonidin_3-O-beta-D-(caffeoyl)-sambubioside + CoA
|
2.3.1
|
–
|
M
|
|
MetaCyc:
RXN-16782
|
|
|
|
cyanidin-3-O-sambubioside + caffeoyl-CoA + H+ <=> cyanidin_3-O-(6-O-caffeoyl)-beta-D-sambubioside + CoA
|
2.3.1
|
–
|
M
|
|
MetaCyc:
RXN-16784
|
|
|
|
caffeoyl-CoA + malonyl-CoA + H+ <=> hispidin + CO2 + CoA
|
2.3.1.M47
|
–
|
|
|
MetaCyc:
RXN-19128
|
|
|
|
3-(3,4-dihydroxyphenyl)-3-hydroxypropanoate <=> caffeoyl-CoA + H2O
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-19743
|
|
|
|
caffeoyl-CoA + 5-hydroxyanthranilate <=> avenanthramide_C + CoA
|
2.3.1.dt
|
–
|
M
|
|
MetaCyc:
RXN-21513
|
|
|
|
delphinidin_3,3',5'-tri-O-beta-D-glucoside + caffeoyl-CoA <=> delphinidin_3-O-glucosyl-5-O-(caffeoylglucoside-3''-O-glucoside) + CoA
|
2.3.1
|
–
|
M
|
|
MetaCyc:
RXN-8232
|
|
|
|
delphinidin_3-O-glucosyl-5-O-(caffeoylglucoside-3''-O-glucoside) + caffeoyl-CoA <=> gentiodelphin + CoA
|
2.3.1
|
–
|
M
|
|
MetaCyc:
RXN-8235
|
|
|
|
caffeoyl-CoA + tyramine <=> CoA + (2E)-3-(3,4-dihydroxyphenyl)-N-[2-(4-hydroxyphenyl)ethyl]prop-2-enamide
|
2.3.1.110
tyramine N-feruloyltransferase
|
–
|
|
|
BRENDA:
BS320297
|
|
|
|
caffeoyl-CoA + D-glucono-1,5-lactone <=> CoA + O-caffeoylglucarolactone
|
2.3.1.132
glucarolactone O-hydroxycinnamoyltransferase
|
–
|
|
|
BRENDA:
BS356075
|
|
|
|
caffeoyl-CoA + anthranilate <=> CoA + N-(3,4-dihydroxycinnamoyl)-anthranilate
|
2.3.1.144
anthranilate N-benzoyltransferase
|
–
|
|
|
BRENDA:
BS420434
|
|
|
|
caffeoyl-CoA + 2 NADH + 2 oxidized_ferredoxin_iron-sulfur_cluster <=> 3,4-dihydroxyphenylpropanoyl-CoA + 2 NAD+ + 2 reduced_ferredoxin_iron-sulfur_cluster
|
1.3.1.108
caffeoyl-CoA reductase
|
–
|
|
|
BRENDA:
BS430808
|
|
|
|
caffeoyl-CoA + agmatine <=> CoA + caffeoylagmatine
|
2.3.1.64
agmatine N4-coumaroyltransferase
|
–
|
|
|
BRENDA:
BS321162
|
|
|
|
caffeoyl-CoA + cadaverine <=> CoA + N-caffeoylcadaverine
|
2.3.1.138
putrescine N-hydroxycinnamoyltransferase
|
–
|
|
|
BRENDA:
BS320495
|
|
|
|
caffeoyl-CoA + 3-Hydroxyanthranilate <=> CoA + 3-caffeoyloxyanthranilate
|
2.3.1.133
shikimate O-hydroxycinnamoyltransferase
|
–
|
|
|
BRENDA:
BS420431
|
|
|
|
caffeoyl-CoA + 3-Hydroxyanthranilate <=> CoA + N-caffeoyl-3-hydroxyanthranilate
|
2.3.1.144
anthranilate N-benzoyltransferase
|
–
|
|
|
BRENDA:
BS420432
|
|
|
|
caffeoyl-CoA + 1,6-diaminohexane <=> CoA + N-caffeoyl-1,6-diaminohexane
|
2.3.1.138
putrescine N-hydroxycinnamoyltransferase
|
–
|
|
|
BRENDA:
BS320498
|
|
|
|
malvidin_3-O-beta-D-glucoside + caffeoyl-CoA <=> CoA + malvidin_3-O-(6-O-caffeoyl)-beta-D-glucoside
|
2.3.1.215
anthocyanidin 3-O-glucoside 6''-O-acyltransferase
|
–
|
|
|
BRENDA:
BS435613
|
|
|
|
caffeoyl-CoA + D-tyrosine <=> CoA + N-caffeoyl-D-tyrosine
|
2.3.1.140
rosmarinate synthase
|
–
|
|
|
BRENDA:
BS420436
|
|
|
|
caffeoyl-CoA + 4-(2-hydroxyethyl)phenol <=> CoA + 2-O-caffeoyltyrosol
|
2.3.1.140
rosmarinate synthase
|
–
|
|
|
BRENDA:
BS455430
|
|
|
|
caffeoyl-CoA + 1,7-Diaminoheptane <=> CoA + N-caffeoyl-1,7-diaminoheptane
|
2.3.1.138
putrescine N-hydroxycinnamoyltransferase
|
–
|
|
|
BRENDA:
BS320499
|
|
|
|
caffeoyl-CoA + D-glucarate <=> CoA + caffeoylglucarate
|
2.3.1.131
glucarate O-hydroxycinnamoyltransferase
|
–
|
|
|
BRENDA:
BS320436
|
|
|
|
caffeoyl-CoA + Mandelate <=> CoA + 2-O-caffeoylmandelate
|
2.3.1.140
rosmarinate synthase
|
–
|
|
|
BRENDA:
BS455428
|
|
|
|
caffeoyl-CoA + 3-(4-hydroxyphenyl)lactate <=> CoA + 2-O-caffeoyl-3-(3,4-dihydroxyphenyl)lactate
|
2.3.1.140
rosmarinate synthase
|
–
|
|
|
BRENDA:
BS420429
|
|
|
|
caffeoyl-CoA + 3-(4-hydroxyphenyl)lactate <=> CoA + 2-O-caffeoyl-3-(4-hydroxyphenyl)lactate
|
2.3.1.140
rosmarinate synthase
|
–
|
|
|
BRENDA:
BS320506
|
|
|
|
caffeoyl-CoA + galactarate <=> CoA + O-caffeoylgalactarate
|
2.3.1.130
galactarate O-hydroxycinnamoyltransferase
|
–
|
|
|
BRENDA:
BS320432
|
|
|
|
caffeoyl-CoA + pelargonidin_3-O-beta-D-glucoside <=> CoA + pelargonidin_3-O-[6-O-caffeoyl-beta-D-glucoside]
|
2.3.1.215
anthocyanidin 3-O-glucoside 6''-O-acyltransferase
|
–
|
|
|
BRENDA:
BS423099
|
|
|
|
caffeoyl-CoA + Phenyllactate <=> CoA + 2-O-caffeoyl-3-phenyllactate
|
2.3.1.140
rosmarinate synthase
|
–
|
|
|
BRENDA:
BS455429
|
|
|
|
caffeoyl-CoA + Tartronate <=> CoA + caffeoyltartronic_acid
|
2.3.1.106
tartronate O-hydroxycinnamoyltransferase
|
–
|
|
|
BRENDA:
BS320272
|
|
|
|
caffeoyl-CoA + 3-(3-methoxy-4-hydroxyphenyl)lactate <=> CoA + 2-O-caffeoyl-3-(3-methoxy-4-hydroxyphenyl)lactate
|
2.3.1.140
rosmarinate synthase
|
–
|
|
|
BRENDA:
BS320509
|
|
|
|
caffeoyl-CoA + 3-(3,4-Dihydroxyphenyl)lactate <=> CoA + rosmarinic_acid
|
2.3.1.140
rosmarinate synthase
|
–
|
|
|
BRENDA:
BS320505
|
|
|
|
caffeoyl-CoA + D-phenyllactate <=> CoA + (R)-2-O-caffeoyl-3-phenyllactate
|
2.3.1.140
rosmarinate synthase
|
–
|
|
|
BRENDA:
BS420435
|
|
|
|
caffeoyl-CoA + chlorogenic_acid <=> cynarin + CO2
|
2.3.1.B33
|
–
|
|
|
BRENDA:
BS455426
|
|
|
|
caffeoyl-CoA + 1,3-diaminopropane <=> CoA + N-caffeoyl-1,3-diaminopropane
|
2.3.1.138
putrescine N-hydroxycinnamoyltransferase
|
–
|
|
|
BRENDA:
BS320496
|
|
|
|
caffeoyl-CoA + cyanidin_3,5-di-O-beta-D-glucoside <=> CoA + cyanidin_3-O-[6-O-caffeoyl-beta-D-glucosyl]-5-O-beta-D-glucoside
|
2.3.1.215
anthocyanidin 3-O-glucoside 6''-O-acyltransferase
|
–
|
|
|
BRENDA:
BS423092
|
|
|
|
caffeoyl-CoA + 3-hydroxybenzoate <=> CoA + 3-caffeoyloxybenzoate
|
2.3.1.133
shikimate O-hydroxycinnamoyltransferase
|
–
|
|
|
BRENDA:
BS420433
|
|
|
|
caffeoyl-CoA + delphinidin_3,5-di-O-beta-D-glucoside <=> CoA + delphinidin_3,5-O-[6-O-caffeoyl-beta-D-diglucoside]
|
2.3.1.215
anthocyanidin 3-O-glucoside 6''-O-acyltransferase
|
–
|
|
|
BRENDA:
BS423094
|
|
|
|
caffeoyl-CoA + 3 malonyl-CoA <=> eriodictyol + 4 CoA + 3 CO2
|
2.3.1.74
chalcone synthase
|
–
|
|
|
BRENDA:
BS321285
|
|
|
|
caffeoyl-CoA + malonyl-CoA <=> 3,3'',4'',5-tetrahydroxystilbene + CoA + CO2
|
2.3.1.146
pinosylvin synthase
2.3.1.95
trihydroxystilbene synthase
|
–
–
|
|
|
BRENDA:
BS321500
|
|